Topic 8 - Management of Surgical Patients with VWD: New Research-based Options

Purpose
Advance healthcare professionals' knowledge of von Willebrand Disease (VWD) in the surgical setting

Target Audience
This activity meets the needs of physicians involved in the care of patients with VWD

Program Overview
Treating patients with VWD can be complicated, especially during surgical procedures. Recent research-based studies on available therapies in the surgical setting have provided a new understanding of how to properly treat and monitor these patients.

This activity has been designed to explore these studies and provide a thorough understanding of the preoperative and postoperative management. It will describe various therapeutic approaches based on the type of VWD during several surgical procedures. It will also review dosing concerns, thrombogenicity, testing and laboratory monitoring after surgical infusions, and supplemental platelet therapy.

Educational Objectives
Upon completion of this activity, participants should be better able to:

  • Explain research-based studies on available therapies for VWD patients in the surgical setting
  • Describe how to properly treat and monitor patients with VWD preoperative and postoperative
  • Review therapeutic approaches for each type of VWD during various surgical procedures
Physician Accreditation Statement
This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint sponsorship of the Postgraduate Institute for Medicine (PIM) and ProMed Institute. PIM is accredited by the ACCME to provide continuing medical education for physicians.

Credit Designation
PIM designates this educational activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)TM. Physicians should only claim credit commensurate with the extent of their participation in the activity.

Disclosure of Conflicts of Interest
Postgraduate Institute for Medicine (PIM) assesses conflict of interest with its instructors, planners, managers and other individuals who are in a position to control the content of CME activities. All relevant conflicts of interest that are identified are thoroughly vetted by PIM for fair balance, scientific objectivity of studies utilized in this activity, and patient care recommendations. PIM is committed to providing its learners with high quality CME activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of a commercial interest.

The faculty reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME activity:

Prasad Mathew, MD.
Advisory Board: Bayer, CSL Behring, Novo Nordisk

Joan Cox Gill, MD
Consulting Fees: CSL Behring, Octapharma, Bayer, Merck
Contracted Research: Baxter, Bayer

The planners and managers reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME activity:

The following PIM planners and managers, Linda Graham, RN, BSN, BA, Jan Hixon, RN, BSN, MA, Trace Hutchison, PharmD, Julia Kirkwood, RN, BSN and Jan Schultz, RN, MSN, CCMEP hereby state that they or their spouse/life partner do not have any financial relationships or relationships to products or devices with any commercial interest related to the content of this activity of any amount during the past 12 months.

The following ProMed Institute planner and manager, Claire Harbeck, MBA, hereby states that she or her spouse/life partner do not have any financial relationships or relationships to products or devices with any commercial interest related to the content of this activity of any amount during the past 12 months.

Method of Participation
There are no fees for participating and receiving CME credit for this activity. During the period 08/2009 through 08/2010 participants must

  1. read the learning objectives and faculty disclosures;
  2. study the educational activity;
  3. complete the posttest by recording the best answer to each question in the answer key on the evaluation form;
  4. complete the evaluation form; and
  5. complete online or mail/fax the evaluation form with answer key to ProMed Institute.

A statement of credit will be issued only upon receipt of a completed activity evaluation form and a completed posttest with a score of 70% or better. Your statement of credit will be provided online.

Media
Internet

Disclosure of Unlabeled Use
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Postgraduate Institute for Medicine (PIM), ProMed Institute, and CSL Behring do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of PIM, ProMed Institute, and CSL Behring. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Disclaimer
Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient's conditions and possible contraindications on dangers in use, review of any applicable manufacturer's product information, and comparison with recommendations of other authorities.

 
Original airdates: May 6, May 14, and
May 22, 2008
Expiration date: August 2010
Estimated time to complete activity: 1 hour
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Agenda

5 minutes—Welcome and Introduction

20 minutes—Treating Patients with VWD Undergoing Surgery: Prospective and Retrospective Studies

Prasad Mathew, MD
Professor, Department of Pediatrics
University of New Mexico
Director, Ted R. Montoya Hemophilia Center
Albuquerque, New Mexico

20 minutes—Preoperative and Postoperative Management of Patients with VWD

Joan Cox Gill, MD
Professor of Pediatrics and Medicine
Medical College of Wisconsin
Director, Comprehensive Center for Bleeding Disorders
The BloodCenter of Wisconsin
Milwaukee, Wisconsin

10 minutes—Question and Answer (Panel)

5 minutes—Closing Remarks


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